Treatment methods for cat atopic dermatitis and how to solve cat skin symptoms!

Treatment methods for cat atopic dermatitis, a method to solve cat skin symptoms! Atopic dermatitis is abbreviated as CAD. The main symptom of CAD is itching, which is manifested as excessive scratching, friction, gnawing and self-licking. Skin erythema can be seen in early symptoms, but most lesions are caused by chronic inflammation and self-scraping, which can cause symptoms of epidermal loss (scratched marks), pigmentation (black skin), mossy (thickened skin, roughness), and damaging hair loss. Atopic dermatitis in cats can be difficult to treat, and sometimes you need a little luck. The incidence of atopic dermatitis is different, and has been reported in some studies to be as high as 73% of all allergic cats, or second only to flea allergies. There may be a hereditary tendency here because some families have higher incidence rates, but no specific genes have been found. There are seasonal and non-seasonal allergies in cats. A study of 66 atopic dermatitis cats found that: 50% have fleas, 58% are non-seasonal, 39% are both seasonal and non-seasonal, and 5% are allergic to pollen only. Dust mites at home are the most common non-seasonal reactions.

Distribution:

Variable, local areas can be on the head, face, ears, neck, medial forelimbs, ventral and lateral body, posterior thighs, and whole body.

Clinical symptoms: itchy papules scab (mildegenerative dermatitis), hairlessness caused by self-damage-barber-type hairlessness (symmetrical hair loss in cats), erosion-exfoliation dermatitis caused by self-damage, eosinophilic granulomatous complex lesions, asthma, combination symptoms. It cannot be distinguished from other allergic symptoms, although there may be seasonality, many cases also have flea allergies, and some have food allergies, and respiratory symptoms are more common in cats.

Care and health methods for atopic dermatitis in cats

Diagnosis:

Intradermal antigen test is more difficult than dogs, and it is more difficult to interpret. In vitro tests are helpful.

Treatment

1, Glucocorticoid

Glucocorticoid is the most commonly used drug to control AD ​​itching. Cautionary dosage and short-term medication can also cause mild side effects in the animal. Many dermatologists usually choose this medicine when other treatments are ineffective. The specific recommended medications are: prednisone, prednisolone and methylprednisolone, 0.5-1mg/kg/day, taken orally for 5-7 consecutive days. Since glucocorticoids are the most effective AD treatment drugs, they are not suitable for long-term use unless there is no other alternative. The anti-itonic mechanism of this type of drug is to inhibit phospholipase A2, a rate-limiting step in the synthesis of prostaglandins and leukotrienes, which effectively blocks the entire inflammatory cascade and quickly relieves itching. Side reactions are equally famous.

Common use for short periods of time: shortness of breath, polyuria, excessive drinking and excessive eating. The side effects vary greatly between individuals, making it difficult for veterinarians to predict. Some cases develop iatrogenic Kuxing syndrome simply because of the use of steroid-containing eye drops, while some cases have multiple injections of long-acting steroids but no clinical side effects. In contrast, choosing oral and injecting short-acting corticosteroids is a routine regimen, and longer-acting injections are safer.

2. Antihistamines

Antihistamines are best used in the early stages of the itching season and are not effective for severe itching. The use of antihistamines, essential fatty acids and topical therapeutic drugs can significantly control the degree of itching in some cases, thereby reducing the incidence of superficial pyoderma and other secondary diseases. First-generation H1 blockers are representative of antihistamines. Due to the characteristics of anticholinergic, side effects of drowsiness or excitation are prone to side effects. The anti-itchi effect of this medicine is difficult to predict, but the risk is very low, so it is suitable for use in most cases. It usually takes 14-21 days to take effect. Through competition inhibition, such drugs can ease the synthesis of leukotrienes and prostaglandins (fatty acids and arachidonic acid are the precursors of both). The metabolites of essential fatty acids are fewer inflammatory substances. When high doses of omega-3 fatty acids are given, the enzyme that occupies the same place can be replaced by arachidonic acid, and its anti-inflammatory mechanism is thus derived. Therefore, taking essential fatty acids at the same time can reduce the dosage of steroids and antihistamines to treat allergies. Some people have investigated that daily oral administration of fish oil containing pentacosapentaenoic acid (EPA, 66mg/kg) also has the above effects.